Scientific production from 2010 to 2018 about the quality control of plant species included in the Brazilian National List of Essential Medicines
DOI:
https://doi.org/10.22239/2317-269x.01547Keywords:
Medicinal plants, Phytomedicines, Bibliometric analysis, Brazilian Unified Health System, RENISUSAbstract
Introduction: The Brazilian Ministry of Health established the National List of Medicinal Plants of Interest to the Unified Health System (Renisus) to encourage scientific research related to a list of 71 plant species with potential to generate new products
for the public health system. However, only 12 of these species are contemplated by the Brazilian National List of Essential Medicines (Rename) and therefore have their respective phytomedicines offered at SUS. In addition, 3 of them are not contemplated in the Brazilian Pharmacopoeia. Objective: This work aims to indicate the possibility of using the available references to elaborate and include the missing monographs in the Brazilian Pharmacopoeia; as well as to assess whether the main government policy to encourage research in the area influenced Brazilian scientific production considering the studied profile. Method: A longitudinal retrospective study was carried out using the Web of Science and Scopus databases regarding the quality control of the 12 plant species contemplated in the Rename by different analytical techniques considering the pre and
post-Renisus periods (pre and post-2010). Results: All evaluated species presented scientific articles describing analytical methods to determine their constituents. Among the evaluated species, 67% had low individual nominal growth (≤ 8 articles) in the pre and post Renisus periods, while the rest showed greater growth (≥ 19 articles). Conclusions: There are available references in the literature with potential analytical methods for the elaboration of the missing pharmacopoeial monographs in the Brazilian compendium. However, the incentive policies may not have had significantly influenced the studied fraction of the Brazilian scientific production.
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