Quality control of the plant drug Calendula officinalis L. available in the city of Ponta Grossa (PR)
Vigil Sanit Debate, Rio de Janeiro, 2024, v.12: e02245 | Published on: 15/10/2024
DOI:
https://doi.org/10.22239/2317-269X.02245Keywords:
Thermal analysis, Flavonoids, Medicinal Plants, PurityAbstract
Introduction: Calendula officinalis L. is a herbaceous plant belonging to the Asteraceae family that contains flowers as parts used to obtain analgesic, anti-inflammatory, antiseptic, healing, and dermoprotective effects. Objective: The objective of the present work was to analyze and characterize samples of C. officinalis, sold in Ponta Grossa (PR), and verify their compliance with current legislation, presenting the quality control provided for by the Brazilian Pharmacopoeia (2019). Method: After selecting the selections, tests were carried out on the quality control of the herbal drug by checking the packaging and labeling, macroscopic and microscopic identification, purity tests, analysis of loss due to desiccation and total ash, thermal analysis, profile of the aqueous extract in thin layer chromatography, and source of flavonoids from secondary metabolites. Results: All samples were identified as C. officinalis and were approved in the chromatographic profile and flavonoid content; however, sample B did not meet the pharmacopoeia purity requirements. Conclusion: Medicinal plants with quality deviations may suffer a significant reduction in their therapeutic effect, in addition to generating possible side and toxic effects.
Downloads
Author Biographies
-
Gabriel Augusto Caixeta Nunes, Faculdade Cesumar de Ponta Grossa (UniCesumar), Ponta Grossa, PR, Brasil
-
Isadora de Jesus Mariano Lacerda, Faculdade Cesumar de Ponta Grossa (UniCesumar), Ponta Grossa, PR, Brasil
-
Juliane Nadal Dias Swiech, Faculdade Cesumar de Ponta Grossa (UniCesumar), Ponta Grossa, PR, Brasil
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Health Surveillance under Debate: Society, Science & Technology
This work is licensed under a Creative Commons Attribution 4.0 International License.
COPYRIGHT ALLOWANCE The author (s) hereinafter designated as the ASSIGNOR hereby assign and transfer, free of charge, the ownership of the copyrights related to this ARTICLE to the Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia (Health Surveillance under Debate: Society, Science & Technology) – Visa em Debate, represented by FUNDAÇÃO OSWALDO CRUZ, established at Av. Brasil, nº 4365, Manguinhos, Rio de Janeiro, RJ, Brazil, CEP 21045-900, under the conditions set out below: (a) The terms and conditions set forth in this Agreement shall apply to the following: 1. The ASSIGNOR declares that they s(he) is (are) the author (s) and owner (s) of the copyrighted property of the ARTICLE submitted. 2. The ASSIGNOR declares that the ARTICLE does not infringe the copyrights and / or other property rights of third parties, that the disclosure of images (if any) has been authorized and that they s(he) assume(s) full moral and / or property liability for its content, before third parties. 3. THE ASSIGNOR assigns and transfers all copyrights relating to the ARTICLE to the ASSIGNEE, especially the rights of editing, publication, translation into another language and reproduction by any process or technique. The ASSIGNEE becomes the exclusive owner of the rights related to the ARTICLE, and any reproduction, totally or partially, is prohibited in any other means of publicity, printed or electronic, without prior written authorization from the ASSIGNEE. 4. The assignment is free and, therefore, there will be no remuneration for the use of the ARTICLE by the ASSIGNEE.
